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Smad-mediated transcription is required for transforming growth factor-beta 1-induced p57(Kip2) proteolysis in osteoblastic cells

These antibodies are used to treat a variety of solid and blood tumors and include anti-CTLA-4 antibodies (ipilimumab), anti-PD-1 antibodies (nivolumab, pembrolizumab), and anti-PD-L1 antibodies (atezolizumab, durvalumab, avelumab)